BareFacedTruth.com | Physician-scientists examine the sometimes ugly truth behind beauty product claims

EXOSOMES IN SKINCARE PART III – We Launched! What a Beautiful Sight.

What a liftoff!  Our name is in lights! In March 2019 and in July 2021, BFT introduced its readers to the rapidly evolving science of exosomes and their potential for […]

A Decade Later, We’re Still Fans of Bone Marrow Mesenchymal Stem Cell Conditioned Media for Anti-Aging Skincare

It’s hard to believe barefacedtruth.com just celebrated its 10 year anniversary. Time does fly when you’re having fun! Your hosts are especially pleased that our readers have enjoyed our message […]

EXOSOMES IN SKINCARE – PART II

In March 2019, BFT introduced our readership to a remarkable class of intercellular signaling messengers called exosomes. These are extraordinarily small “packets” of potent bio-signaling molecules secreted by all types […]

Safety of Topical Human Biosignals in Skincare – Part 2 (Including information re: FDA regulatory notifications)

Two decades have passed since the first skincare product containing human cell-culture-derived biosignals was launched in 2001. TNS Recovery Complex by SkinMedica was the pioneer that established a new class […]

We’re Talking Red Deer, Not Red-Nosed Deer.

A reader recently asked about the cancer-causing potential of a skincare product she purchased from a company in Singapore (CALECIM). It contains laboratory culture-derived bio-signaling molecules derived from red deer […]

Scientific Misconduct in Medical Aesthetics Research (Part 2)

WARNING: Honesty in Scientific Publishing is Not Always a Given. Nearly everyone, professionals and lay readers alike, assumes there is predictable and reliable honesty in published scientific literature. If not, […]

Scientific Misconduct in Medical Aesthetics Research (Part 1)

Introduction As our loyal readers well know, BFT is no stranger to controversy. From our launch in 2011, the mission of barefacedtruth.com has been to inform, educate, and entertain – […]

Still hiding from pigment issues? There’s a new deep-science approach.

Abnormality in pigment is one of the most common topics readers inquire about on BFT. Most frequently it has to do with hyperpigmentation that results from an inflammatory insult (PIH) […]

Safety of Topical Human Biosignals in Skincare – Part 1

Topical skincare products containing cell culture-derived and/or synthesized human growth factors and cytokines have been available to consumers for two decades. The first such product contained conditioned media derived from […]

“Fool me once, shame on you. Fool me twice, shame on me.”

This old adage only applies when you know you are being fooled. If cleaver marketing with coined slogans and verbiage in involved, it is quite possible to be fooled over […]

EXOSOMES – very small, very mighty, very important.

Exosomes are a fascinating area of research in healthcare. Discovered 30 years ago and initially thought to be the means by which cells “eject” waste products and debris, they are […]

It’s alive. Our hair re-growth product is alive! (Hair-Part IV)

Please forgive us. Sometimes when we don our BFT host hats, it’s impossible to remain entirely dispassionate about our daytime work. Today is one of those days. We are enthused […]

OMG! My Sweet Tooth is Aging My Skin!

Quite often, questions come from our BFT readers that convince us we have an extraordinarily inquisitive and bright readership, something for which we are very grateful. It convinces us our […]

DNA Repair Enzymes: – Part II: Positive Benefits on Skin? Positively!

DNA damage and repair are complex topics with certain details necessary and unavoidable to cover the subject. The BFT audience is comprised of readers with sophisticated science backgrounds and others […]

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