NEWS AND VIEWS JANUARY 6, 2012
According to a recent study, epidermal stem cells do not operate continuously to renew skin cells , but instead cycle between dormancy and activation. Turns out that these cells have their own internal clock genes that oscillate through day-night cycles. These rhythms assure that during the day, when sun exposure can lead to DNA damage (oncogenesis), there are far fewer cell divisions than at night when the danger has passed. If you interfere with these clock genes it can lead to stem cell arrhythmia, premature skin aging, and the development of skin cancers. These studies were done in mice, so it may not be exactly the same in humans. But we do know that humans share these clock genes.
This adds further evidence to the notion of sleep (dark cycle behaviors) being a time of skin renewal. Products that target regenerative epidermal pathways might do well to keep this in mind, providing maximum regenerative ingredient at night, and focus more on prevention of further damage (e.g. sunblocks, antioxidants) during the day. We will talk about this more in a post about DNA repair enzymes.
NEWS AND VIEWS JANUARY 5, 2012
There are false claims, and then there are false associations. We have noted a trend in the anti-aging products world toward making false associations about products being sold by trying to fool buyers into thinking that their science is so mainstream and legitimate that it has even been awarded a Nobel prize. *Here is one example now on display at TIA:
- RESPECT TRUTHFULNESS (deception objection)
- Never directly intend to deceive
- Never use simply untrue advertising
- Do not distort the truth by implying things that are not so or withholding relevant facts
NEWS AND VIEWS JANUARY 4, 2012
Part of our mission at BFT is to point out contrasts. Below are two brief stories in the news today. One reflects the promise and hope of stem cells in reversing aging. The other reflects a tendency for some unscrupulous persons to profit from leading edge science through fraud, lies, and victimization.
Stem cells and aging
“Researchers at the University of Helsinki are finding more clues to understanding the aging process. A fresh study, which sheds new light on what happens in the body as we age, is published in the latest issue of Cell Metabolism out on Wednesday.
Focused on aging-related tissue degeneration, Anu Wartiovaara’s research group studied mice exhibiting early signs of aging: thinning skin, graying hair, balding, osteoporosis and anemia.
Scientists provided evidence that mitochondrial mutation can adversely impact cell function. To combat the symptoms of old age, researchers used antioxidant treatments to improve stem cell function. Wartiovaara, however, emphasises that breakthroughs with mice may not necessarily translate to humans.
‘But we can say that antioxidants affect stem cell function,’ she explains, adding that more research is necessary before prescribing antioxidants to slow the hands of time. ”
Men charged with selling miracle stem-cell cures to terminally ill patients
Four men allegedly conned more than $1.5M out of terminally ill patients by hawking miracle stem-cell cures, Reuters reported.
Three men were arrested and another is on the run, the FBI reported, after all four were charged with 39 counts of mail fraud and illegally manufacturing, distributing and selling stem cells and related procedures. The group launched the three-year scam in March 2007, allegedly working together to convince hopeless patients to undergo illegal procedures they promised would treat “incurable diseases,” according to the FBI. “This investigation identified a scheme whereby the suffering and hopes of victims in extreme medical need were used and manipulated for personal profit. “The predatory and opportunistic nature of the crimes alleged in this indictment mirrors images from science fiction.”